Algorithm Aids Management of Hypersensitivity Reactions After Vaccination
A detailed algorithm offers a rational and organized strategy to evaluate and treat patients with suspected immediate hypersensitivity reactions after vaccination. <br /> <i>Medscape Medical News</i>

Do Corticosteroids Reduce Mortality in Pediatric Patients With Bacterial Meningitis?
A study published in the May 7, 2008, issue of JAMA looks at whether steroids confer a mortality benefit on children with meningitis. <br /> <i>Medscape Pediatrics</i>

Parechoviruses Linked With Meningitis and Sepsis-Like Illness in Children
Human parechoviruses are an important viral cause of sepsis-like illness and meningitis in young children, according to Dutch researchers. <br /> <i>Reuters Health Information</i>

Insidious Swelling in the Neck of a 45-Year-Old Man
A 45-year-old man complains of gradual swelling in his neck over the past 6 months; he has a nontender, nonerythematous, fluctuant mass in the midline of the lower neck. He has not experienced any pain, fevers, difficulty swallowing, or alteration of his voice. What is the diagnosis? <br /> <i>eMedicine Case Presentations</i>

Pelvic Surgery in A Child With Hemophilia C: A rare Disease, A Real Challenge, A Simple Solution
Patients often have no spontaneous bleeding, but they can have serious and life-threatening bleeding with trauma or when undergoing surgical procedures. <br /> <i>Transfusion Alternatives in Transfusion Medicine</i>

Bisphenol A: Some Concerns Remain
Scientists from the National Toxicology Program outline concerns in their final bisphenol A safety report, but the number of concerns is lower than previously noted. <br /> <i>WebMD Health News</i>

Montelukast Not Linked to Suicide, Depression
A review of data from three randomized trials revealed no evidence that use of the allergy/asthma drug montelukast (Singular) increases the risk of depression or suicide, according to a report by the American Lung Association in the upcoming issue of the Journal of Allergy and Clinical Immunology. <br /> <i>Reuters Health Information</i>

Down Syndrome Patients Have Worse ALL Outcomes
Down syndrome patients who develop acute lymphoblastic leukemia (ALL) have worse treatment outcomes than patients without this genetic abnormality, according to a report in the August 1st issue of Cancer. <br /> <i>Reuters Health Information</i>

Strong Evidence Rules Out Link Between MMR Vaccine and Autism
Researchers released the latest evidence Wednesday showing no association between vaccination with the measles, mumps and rubella (MMR) vaccine and autism spectrum disorders with gastrointestinal (GI) disturbances. The pendulum has swung back and forth on the issue, but these findings, for this vaccine, do not support a link. <br /> <i>Reuters Health Information</i>

HPV Vaccine Is Most Cost Effective for Preadolescent Girls
The results of a cost analysis regarding efficacy of the HPV vaccine may have been oversimplified and even misinterpreted by the lay press. <br /> <i>Medscape Hematology-Oncology</i>

Emergency Department Visits for Cough and Cold Medication-Related Adverse Drug Events in Children
A study published in the April 2008 issue of Pediatrics finds unsupervised ingestions and overdoses in this age group. <br /> <i>Medscape Pediatrics</i>

Hand Hygiene: How Can We Improve?
Lisa Maragakis, MD, reviews in her videoblog the serious challenges of measuring and improving hand hygiene compliance in the healthcare setting. <br /> <i>Medscape Infectious Diseases</i>

Plain-Language Pictogram Reduces Liquid Medication Dosing Errors in Children
A study shows that a pictogram intervention is effective in reducing medication dosing errors and improving medication adherence for caregivers of children who received liquid medication. <br /> <i>Medscape Medical News</i>

Ondansetron Therapy May Improve Outcomes in Children With Gastroenteritis
Ondansetron decreased the risk for persistent vomiting, intravenous fluid use, and hospitalizations in children presenting to the emergency department for vomiting from gastroenteritis. <br /> <i>Medscape Medical News</i>

Postnatal Growth Linked to Blood Pressure in Young Adulthood
A study shows that only immediate postnatal growth predicts diastolic blood pressure in term births, whereas both birth weight and postnatal growth are associated with systolic blood pressure. <br /> <i>Medscape Medical News</i>

Should You Lower the Temperature in Children With Brain Injury?
Commentary on a study on the effects of hypothermia in children following brain injury, published June 2008 in The New England Journal of Surgery. <br /> <i>Medscape General Surgery</i>

Filaggrin Null Mutations Linked With Asthma Exacerbations
Asthmatic children and young adults with null mutations of the filaggrin (FLG) gene, which encodes an epidermal structural protein, are at increased risk of asthma exacerbations, UK researchers report in the September issue of Allergy. They note that about 9% of people of European origin have this mutation. <br /> <i>Reuters Health Information</i>

Course of Pediatric Crohn's Less Complicated With Early Onset Than With Later Onset
Children who develop Crohn's disease before the age of 5 years have a less complicated disease course than children with disease onset after age 6, according to a report in the August issue of the American Journal of Gastroenterology. <br /> <i>Reuters Health Information</i>

C-Section Cuts Mortality of Very Preterm Infants
Cesarean section seems to improve the survival of most infants delivered at 22 to 25 weeks of gestation, new research shows. Moreover, this finding was noted independent of several risk factors indicating a need for the procedure. <br /> <i>Reuters Health Information</i>

Electronic Personal Health Records: Should Doctors Worry?
Matthew K. Wynia, MD, MPH, FACP, Director, The Institute for Ethics, American Medical Association, Chicago, Illinois, describes many ethical twists in electronic health records. <br /> <i>The Medscape Journal of Medicine</i>